13 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... - infiltrates (anemia ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... , deficiency anemia ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm Acute ... • Myloid (AML ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
—100-fold with acute ... hepatocytes; in chronic ... deficiency - Anemia ... anemia; blood loss ... the hepatorenal syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... Episcleritis Signs ... , breast CA - Hematologic ... - CBC may also ... #oncology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
, erythema and WBC ... the time course (acute ... noninflammatory Signs ... Morning stiffness lasting ... Diagnosis #MSK #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Acute ... Screening Tests for Chronic ... Arthritis #laboratory #workup