53 results
Mechanisms of thiazide diuretic side effects

Dr. Muner Mohamed @MunerMohamed1

#thiazide #diuretic #pharmacology #pathophysiology #sideeffects #adverseeffects #nephrology
thiazide #diuretic #pharmacology ... #pathophysiology ... #sideeffects #adverseeffects ... #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... cotransporter, K channel, Cl ... barrtin (recruits Cl ... Thiazide-sensitive Na—Cl ... #Differential #Table
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
- MCA - ACA ... - AICA - PCA ... Localization #Effects #Neurology ... #Diagnosis #Table ... Review in Clinical Neurology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology #
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
filtered Na+/K+/Cl ... filtered Na+ and Cl ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypertensive: • High Al ... Normotensive: • UCl ... Post-hypercapnia • UCl ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Diagnosis Algorithm Cause ... intoxication Cause ... pressure: - Cl ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
+, Mg2+, Ca2+, Cl ... electrolytes #effects #pharmacology ... #comparison #table