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differential treatment algorithm lupus testing ana antinuclear syndrome systemic antibody erythematosus oncology patterns antibodies causes classification summary table thrombocytopenia vasculitis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Drug-induced SLE ... biliary cirrhosis (PBC ... syndrome Anti-Scl ... #diagnosis #table ... #rheumatology #
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... pattern: - SjS, SLE ... Speckled: - SLE ... #differential #diagnosis ... #rheumatology
Diagnostic algorithm for a child or adolescent with suspected pulmonary hypertension. CHD, congenital heart disease; CPET,
Diagnostic algorithm ... congenital heart disease ... hypertension; PCH ... #Diagnosis #Peds ... #Hypertension #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... : Chronic disease ... Erythematosus #Diagnosis ... #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... rheumatoid arthritis SLE ... LungDisease #CTILD #Diagnosis ... Comparison #Table #Pulmonary ... #Rheumatology #
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
• CD4 < 200: PCP ... Fungal, AFB), TB PCR ... sputum, PCP DFA ... Infectious Diseases ... #diagnosis #evaluation
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
• Specific for SLE ... Erythematosus #SLE ... #Summary #diagnosis ... #rheumatology # ... management
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Drug-associated, PCH ... , Drugs, Liver Disease ... #Differential #Diagnosis ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... but elevated as disease ... Diagnosis: • ... , IgG4 related disease ... #workup #hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... ), PAH (pulmonary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
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