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management differential lupus erythematosus oncology sle disease table algorithm dermatology vasculitis causes classification comparison antibodies antinuclear autoantibodies peds purpura signs
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... LAC) • Sjogren Syndrome ... • Scleroderma (Systemic ... Autoantibodies #Rheumatology ... #diagnosis #associations
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... first-line treatment ... Microangiopathy #thrombocytopenic ... #Comparison #Diagnosis ... #Table #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
suspect underlying hematologic ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Thrombocytopenic ... Purpura (TTP) Diagnosis ... soon as TTP is diagnosed ... #rheumatology # ... hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... thrombocytopenia ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... SLE), Sjogren's Syndrome ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Demyelinating syndromes ... Leucopenia/lymphopenia, Thrombocytopenia ... signs #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Antinuclear (ANA ... block • Sjogren syndrome ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Acute bacterial and ... #Algorithm #hematology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
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