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lupus dermatology erythematosus ana antibody antinuclear management nuclear patterns systemic testing vasculitis autoimmune cd4 classification clues comparison cytoplasmic dermatologic druginduced
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... • SLE • Human ... #rashes #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Manifestations: Malar rash ... Photosensitivity, Alopecia ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... Scl70 (in some cases ... -70 (in some cases ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... #Diagnosis #hematology ... #rheumatology #
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... including in children (pediatric ... #sle #clues #system ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... and permanent alopecia ... Differential ... • Nonscarring alopecia ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Discontinuation of causal ... Photosensitivity, Alopecia ... comparison #table #rheumatology ... #diagnosis #management
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... reticularis Differential ... #rash #diagnosis ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Homogeneous pattern: • SLE ... Scl70 (in some cases ... pattern: • SjS, SLE ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Lymphocytopenia DIAGNOSTIC ... Autoimmune (Sjogren, SLE ... #diagnosis #hematology ... #Differential # ... Causes #lymphocytopenia
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