11 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Cholestatic Liver Injury ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... ) - Differential ... Drug-induced liver injury ... #Differential # ... Diagnosis #hepatology
Hepatic Masses on MRI - Differential Diagnosis by MRI Findings

Masses: Hemangioma, Adenoma, FNH, HCC, Fibrolamellar HCC,
- Differential ... Diagnosis by MRI ... #differential # ... diagnosis #liver #hepatology ... #radiology #mass
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Drug-induced Liver Injury ... dose dependent injury ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential ... Differential Diagnosis ... #Differential # ... Diagnosis #hepatology ... Transaminitis #LFTs
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Resonance Imaging (MRI ... #Contrast #CT #MRI ... #POCUS #radiology ... #differential # ... table #appearance #hepatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
XR, MRI to ... difficult to see on XR ... • Differentiate ... SickleCell #Disease #differential ... diagnosis #causes #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... ALF): • Liver injury ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
5 or elevated Cr ... common • Imaging: CXR ... initiation • Differential ... fluid overload, PCC ... diagnosis #management #hematology