9 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Scl70 (in some cases ... -70 (in some cases ... body-like: - Neurologic ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Intravascular Hemolysis - Differential ... circulation - Infections ... Cold AIHA • PCH ... #Hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
hemorrhage • CSF PCR ... Toxoplasma gondii PCR ... Demyelinating disease caused ... • JC-virus PCR ... Enhancement • PCR
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
toxo IgG • CNS PCR ... splenomegaly Other infections ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
but important causes ... factors: - Serology ... ribosomal RNA PCR ... - PCR for ... Endocarditis #diagnosis #differential
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
lumbar spine • MCC ... - Emergency Causes ... constipation Differential ... #diagnosis #causes ... #neurology
Cytomegalovirus (CMV) in HIV-AIDS Patients
Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family.
CMV infection: virus isolation or detection
CMV infection: virus ... : Quantitative PCR ... 50 or less: • Neurologic ... Retinitis (Most common cause ... AIDS #diagnosis #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Miller Fischer and PCB ... immunologic assay - MuSK ... precipitated by: Drugs, infection ... diagnosis #management #neurology
Causes of Myoclonus - Differential Diagnosis
LOCALIZATION:
 • Cortical: Focal/multifocal: Distal UL+ Face, Action/sensitive induced
 • Sub-Cortical:
Causes of Myoclonus ... - Differential ... Malaria, Syphilis, PML ... Inflammatory (MS ... #neurology