20 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... suspect underlying hematologic ... Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology # ... treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
REBEL Review 90: Weight Based 4 Factor PCC Dosing 

#Hematology #Management #Table #4FactorPCC #REBELReview #Pharmacology #Dosing
Based 4 Factor PCC ... Dosing #Hematology ... #Management #Table ... #REBELReview #Pharmacology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Criteria for Sweet Syndrome ... Excellent response to treatment ... count >10 x 10^3/pL ... Criteria #Diagnosis #Hematology ... #Dermatology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
based primarily on clinical ... Estimates of the clinical ... and to adjust treatment ... Diagnosis #Management #Hematology ... Thrombocytopenia #Algorithm
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... fluid overload, PCC ... diagnosis #management #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... microglobulin Treatment ... • Richter’s Syndrome ... Transform to DLBCL, PML ... workup #oncology #hematology