14 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #medications #druginduced
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... thiazidic, PPI, ACE ... 40, F:M 9:1 • Clinical ... Lupusreference #druginduced ... #table #rheumatology
Medial Meniscus Bucket Handle Tear - MSK Radiology
Imaging Findings:
 • Truncation of the medial meniscus on
Handle Tear - MSK Radiology ... The "double PCL ... parallel to the PCL ... Differential diagnosis ... Tear #knee #mri #clinical
Mucoid Degeneration of the ACL
Imaging Findings:
 • T2-hyperintense fluid-signal within the enlarged ACL on both the
Degeneration of the ACL ... within the enlarged ACL ... Differential Diagnosis ... • ACL ganglion ... #Radiology #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... erythematosus (ACLE ... permanent alopecia Differential ... lymphoproliferative syndrome Clinical ... La, anti-Jo-1, SCL
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... symptoms - Pel-Ebstein ... involvement Differential ... Malignancies (eg CML, ALL ... #hematology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
pattern: • SjS, SLE ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
CD4 Lymphopenia (ICL ... DIAGNOSTIC CRITERIA FOR ICL ... Autoimmune (Sjogren, SLE ... #Lymphopenia #ICL ... #Differential #
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
with drug-induced SLE ... Lupusreference #DrugInduced ... #SLE #Systemic ... medications #drugs #pharmacology ... #risk #differential