18 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
the Nephron #DrugInduced ... AcuteKidneyInjury #AKI #Nephrology ... #Pathophysiology ... #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... #medications #druginduced
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... syndrome - Na-K-2Cl ... receptor Distal renal ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... - Diarrhea • RENAL ... gas transport, renal ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
• Increased renal ... Hypoperfusion • Reduced renal ... release • ↓ Cl ... syndrome #Mechanisms #pathophysiology ... #nephrology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Injury • Pre-Renal ... @kdjhaveri #DrugInduced ... #KidneyInjury #differential ... diagnosis #algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... • High Urine Cl ... hyperaldosteronism • High PRA: Renal ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... • High Urine Cl ... hyperaldosteronism • High PRA: Renal ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #Nephrology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Kat_Watson #DrugInduced ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- Urine Na/K/Cl ... protein/Cr - Renal ... - 45% - Pre-renal ... AcuteKidneyInjury #AKI #Nephrology ... Algorithm #Causes #Differential