26 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
, autoimmune hepatitis ... syndrome Anti-Scl ... #diagnosis #table ... #rheumatology # ... antibodies
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... • Serology for hepatitis ... #Differential #Diagnosis ... #Algorithm #Causes
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Thyroid, Autoimmune Hepatitis ... ANA #patterns #rheumatology ... #diagnosis #differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... Differential Diaqnoses ... hepatomegaly, hepatitis ... #diagnosis #management ... #treatment #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... Noninfectious hepatitis ... La, anti-Jo-1, SCL ... -70, RNP antibodies
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... Epstein-Barr Virus • Hepatitis ... Arthritis • SLE ... Obstructive Pulmonary Disease ... Myasthenia Gravis Pharmacologic
Lyme Disease - Diagnosis and Management Summary

Lyme Disease Epidemiology:
- Spirochete
- Reservoir: small mammals & birds
- Transmitted
Lyme Disease - Diagnosis ... Rash: distinctive ... Treatment: 1. ... cefotaxime or PCN ... #treatment
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... in drug-induced SLE ... scleroderma) - Anti-Scl ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... involvement 3% SLE-Related ... Auto-Antibodies ... Lupusreference #SLE ... #differential #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... Manifestations: Malar rash ... life-threatening • Treatment ... Evolution: Chronic disease ... Erythematosus #Diagnosis