35 results
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
resistance to antibiotics ... like PCN and cephalosporins ... the PBPS so that PCN ... THIS CAN BE OVERCOME ... Proteins #AMR #PBP #pharmacology
Outpatient Treatment of with Community-Acquired Pneumonia (CAP)
No comorbidities or risk factors for MRSA or Pseudomonas aeruginosa:
Outpatient Treatment ... IDSA #Outpatient #CAP ... Acquired #Pneumonia #Antibiotics ... #Treatment #Regimen ... Management #Guidelines #pharmacology
Oral Antibiotics for Acne - Indicated for Moderate-to-Severe Acne 
First-Line Drug Class: Tetracyclines 

In the last
reviewed mild acne treatment ... These can be used ... specifically for acne treatment ... We can also pulse-dose ... #Pharmacology #
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Clindamycin in case of PCN ... treatment until ... Lung Abscess Differential ... Abscess #pulmonary #differential
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Failure - Differential ... Pseudo-cellulitis / "CAP ... Immunocompromise Treatment ... • Secondary to Treatment ... #Failure #Differential
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
convoluted tubule (PCT ... filtered Na+/K+/CA2 ... filtered Na+/K+/Cl ... Segments #Function #Pathophysiology ... Tubules #Table #Pharmacology
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
anticholinergics, amantadine, antibiotics ... /insecticides, PCP ... Medication #Causes #Differential ... #Pharmacology #
Medical Treatment Algorithm for Chronic Obstructive Pulmonary Disease
Initial medical treatment of chronic obstructive pulmonary disease (COPD)
Medical Treatment ... Initial medical treatment ... corticosteroids, antibiotics ... #COPD #Treatment ... SABA #SAMA #ICS #Pharmacology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
by many drugs & can ... vascular permeability can ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology