PCL test shoulder diagnosis hematology disease workup rheumatology signs symptoms sle antibodies

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34 results

Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA

- Drug-induced SLE ... syndrome Anti-Scl ... #diagnosis #table ... #rheumatology # ... antibodies

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

and Workup History ... (GI symptoms/endemic ... , ANA (e.g., SLE ... anti-phospholipid antibodies ... #hematology

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Cold Sensitive Antibodies ... [PCH] 3. ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... healthy adults, and should ... context of other symptoms ... ANA #patterns #rheumatology ... #diagnosis #differential

Systemic Lupus Erythematosus - Diagnosis
Manifestations:
- Arthritis 69%
- Malar rash 40%
- Fever 36%
-

Auto-Antibodies ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology

Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of

Rheumatology Workup ... double-stranded DNA antibodies ... should be obtained ... #diagnosis #testing ... #Rheumatology

ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
• Systemic lupus erythematosus
1. Anti-dsDNA

Antineutrophil cytoplasmic antibodies ... in drug-induced SLE ... scleroderma) - Anti-Scl ... Antineutrophil #antibodies ... #diagnosis #rheumatology

Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin

Systemic Lupus (SLE ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology

Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3

Multi-system autoimmune disease ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

Antinuclear antibodies ... Association with disease ... clinically suspected, tests ... erythematosus #diagnosis ... #rheumatology #

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