32 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... syndrome Anti-Scl ... #diagnosis #table ... #rheumatology # ... antibodies
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... B12 - Anti-IF Antibodies ... Liver Function Tests ... Liver Function Tests ... Algorithm #Causes #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Sensitive Antibodies ... [PCH] 3. ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Disorientation, vertigo Diagnostic ... test, TempTest ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... scleroderma) - Anti-Scl ... Antineutrophil #antibodies ... #diagnosis #rheumatology ... #diseases
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... K), H. pylori test ... anti-phospholipid antibodies ... (CVID, WAS), (neurologic ... Causes #Workup #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... and these should ... splenomegaly, abnormal neurology ... Rheumatology ... Peds #Pediatrics #Diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Drug-associated, PCH ... , Drugs, Liver Disease ... Laboratory Tests ... #hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... healthy adults, and should ... ANA #patterns #rheumatology ... #diagnosis #differential