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Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
) • AKI: BUN/Cr ... • LDH ↑ • Hyperkalemia ... Hypocalcemia/Late - Hypercalcemia ... several times per ... causes #treatment #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
HYPOTENSION -> renal ... renal ischemia ... Cast formation: Renal ... several times per ... Dialysis for severe hyperkalemia
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Framework Pre-Renal ... Distributive Shock, HRS, Hypercalcemia ... Acute #Kidney #Injury ... Differential #Diagnosis #nephrology
Osborn waves - positive deflections at the J point (negative in aVR and V1) with a
people with high hypercalcemia ... , brain injury, ... This EKG was recorded ... Cardiology #diagnosis #CriticalCare ... Electrocardiogram #ECG
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Trauma/Crush injury ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
Checklist Approach to Hypokalemia

Consider risk factors for arrhythmia:
 - EKG changes (especially QT prolongation)
 - Digoxin
Checklist Approach to Hypokalemia ... 3.5 - Severe renal ... monitoring depend on renal ... monitoring depend on renal ... #Management #CriticalCare
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
to Acute Kidney Injury ... Cl/urea/protein/Cr ... - Renal/bladder ... US w/ PVR - ... AcuteKidneyInjury #AKI #Nephrology
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
Renal Tubular Acidosis ... Increased Serum K = Hyperkalemic ... Renal Tubular Acidosis ... Tubulointerstitial injury ... Diagnosis #Algorithm #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
of Acute Kidney Injury ... thromboembolism, renal ... tumors INTRINSINC RENAL ... Acute Tubular Injury ... Differential #Diagnosis #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, rhabdo/crush injury ... Excretion: - Renal ... heparinized tube) • ECG ... 15 suggests ↓ renal ... Treatment #potassium #nephrology