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hematology management differential oncology algorithm causes leukemia abnormal aids allergy amyloid amyloidosis associated atlas beaus blood cancer cardiology cll common
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... -> AML: Blast crises ... Lymphadenopathy AML ... cutaneous plaques) AML ... smear: Blasts APML
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Acute • Myloid (AML ... - CD7, CD3 Chronic ... Blood #Disorders #hematology ... #Differential #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... Infection (sepsis), PE ... #APML #diagnosis
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
- Differential Diagnosis ... ), Heme malig (AML ... , CML, T-cell leuk ... insufficiency, Chronic ... #Differential #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... Marrow Failure • Chronic ... progression to AML ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... Transform to DLBCL, PML
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
is similar to PML ... well-defined than PML ... Diagnosis: MRI ... etiologies and PML ... syndrome of HAD
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Bronchiectasis, Chronic ... Clinical suspicion ... Amyloidosis Clinical ... : • Nephrotic syndrome ... Carpal tunnel syndrome
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Well-conditioned athletes Pathologic ... disorders - Chronic ... Arteriovenous fistula ... • Mitchell et al ... Acute Coronary Syndrome
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... Autoimmunity • Chronic ... : • Nephrotic syndrome ... Malignancies • Chronic
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