24 results
diagnosis differential syndrome hemophagocytic lymphohistiocytosis treatment algorithm blood hemeonc lad leukemia lymphadenopathy mds myelodysplastic product reactions rheumatology activation alopecia anemia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Alloimmune • anti-HLA ... Vasculitis • Infection ... Prosthetic Heart ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Still disease, Infection ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Anterior • Infection ... Axillary: • Infection ... (In absence of infection ... pathologic): • Infection ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Pseudotumor - Infectious ... History of Bleeding, Infection ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... can mimic common infections ... Treatment: • Infection ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... #treatment #hematology ... #oncology
Tinea Versicolor (Pityriasis versicolor) NOT a dermatophyte infection Caused by saprophytic, lipid-dependent yeasts Clinical •
a dermatophyte infection ... Caused by saprophytic ... meatballs appearance Management ... Tinea #Versicolor #Dermatology ... SkinRash #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
steroids • In mild cases ... associated with infection ... Options for severe cases ... #Treatment #management ... #hematology
Kerion Raised, boggy lesion with heaped up purulent nodules Caused by host's response to a fungal ringworm
purulent nodules Caused ... fungal ringworm infection ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... hypersensitivity syndromes • HLH ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
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