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hematology causes algorithm management ana antibody antinuclear chronic diffuse disorders focal leukemia localized nuclear patterns rheumatology workup abdominal abscess agglutinin
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
- Differential ... Diagnosis Algorithm ... #LAD #Differential ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... the peripheral blood ... activity • ↓ LAP ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse Lymphadenopathy ... Diagnosis Algorithm ... #LAD #Differential ... #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
- Differential ... Diagnosis Algorithm ... #LAD #Differential ... #Causes #Hematology ... #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - Markers and Differential ... Diagnosis Algorithm ... Acute • Myloid (AML ... ALL) - PAS, TdT Lymphadenopathy
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... initiation • Differential ... fluid overload, PCC ... Differentiation #Syndrome #APML ... #hematology #oncology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... 60 (Ro60), SSB (La ... conditions - Sp-100, PML ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral blood ... smear, HIV/HCV testing ... - Lab for decreased ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Lymphocytosis: Absolute blood ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Positive Coombs testing ... Immunoglobulin M (IgM) • Blood ... younger pts) Differential ... sensitize red blood ... hemolytic #anemia #hematology
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