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diagnosis hematology algorithm causes workup ana anemia antibody antinuclear diffuse focal hemolytic leukemia localized management monoclonal nuclear patterns agglutinin blood
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
and Localized Lymphadenopathy ... - Differential ... #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Acute • Myloid (AML ... ALL) - PAS, TdT Lymphadenopathy ... #hematology #Markers ... #Differential #
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse Lymphadenopathy ... Lymphoma #Diffuse #Lymphadenopathy ... #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized Lymphadenopathy ... - Differential ... #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... Significant ↓ PLT ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... smear, HIV/HCV testing ... - Lab for decreased ... #Differential # ... Causes #Workup #hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody Testing ... 60 (Ro60), SSB (La ... conditions - Sp-100, PML ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
initiation • Differential ... fluid overload, PCC ... Differentiation #Syndrome #APML ... diagnosis #management #hematology ... #oncology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... nucleotidase deficiency, lead ... Consider RBC membrane disorder ... Algorithm #workup #hematology ... #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Positive Coombs testing ... younger pts) Differential ... hemolytic #anemia #hematology
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