21 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Patterns Nuclear ... pattern: - PBC ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Scl70 (in some cases ... : • SSc, PBC/SSc ... ) Nuclear dots pattern ... : • PBC, DM, other ... #diagnosis #rheumatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
hepatocellular pattern ... though cholestatic pattern ... reported (eg AIH-PBC ... Autoantibodies: Auto-Nuclear ... regarding need for treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology ... #oncology
Orthopedic Essentials - Spinal Trauma and Spine Classification 
DENIS THREE COLUMN CONCEPT
Anterior column:
Ligamentum flavum PC ... fractures: Don't cause ... Ligamentous complex (PLC ... Cauda equina Treatment ... #Orthopedics #diagnosis
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... of PCN allergy ... residual lesion or is clear ... #differential #causes ... #management #treatment
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
12.5, WBC 14, Plt ... The table below ... LBRF can be diagnosed ... can be used for diagnosis ... initiation of treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... Drugs, Unknown cause ... Treatment: • ... #management #treatment ... #summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Usual therapeutic management ... sle #comparison #table ... #rheumatology # ... diagnosis #management