22 results
differential treatment lupus oncology sle ana antibodies antibody antinuclear disease erythematosus myositis nuclear patterns systemic testing anemia aplastic associations autoantibodies
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - PBC ... , SSc, PBC/SSc OS ... , PBC/SjS OS ... #differential #diagnosis ... #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... fluid overload, PCC ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Anti-Synthetase Syndrome ... : Jo-1, PL7, PL12 ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
biliary cirrhosis (PBC ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... gastric tumors • Hematology ... #hematology
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
12.5, WBC 14, Plt ... Syndrome: 3d of ... The table below ... or PenG 800K U IM ... microscopy #pathology #clinical
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
pattern: • SSc, PBC ... dots pattern: • PBC ... conditions • Sp-100, PML ... #differential #diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... CNS #neurology #rheumatology ... #management #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... ) Differential Diagnosis ... #diagnosis #management ... signs #symptoms #rheumatology
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