32 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... fluid overload, PCC ... #diagnosis #management ... #hematology #oncology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - PBC ... , SSc, PBC/SSc OS ... , PBC/SjS OS ... SjS, SLE, RA, PBC ... Cytoplasmic #Patterns #differential
Kerion
Raised, boggy lesion with heaped up purulent nodules 
Caused by host's response to a fungal ringworm
purulent nodules Caused ... mentagrophytes) Clinical ... Lymphadenopathy Treatment ... Griseofulvin #Kerion #Dermatology ... #Diagnosis #Management
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Pediatrics Patient - Differential ... elevated rim (In POC ... not be seen try focus ... gabrieltalledop #dermatology ... arthritis #skin #differential
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
reported (eg AIH-PBC ... Hepatitis (eg Viral) Management ... regarding need for treatment ... AIH #Diagnosis #Management ... #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
heparin-PF4 complex → plt ... hypercoagulable state and plt ... Diagnosis: • Clinical ... non-heparin A/C if clinical ... #Treatment #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess - Clinical ... of PCN allergy ... Lung Abscess Differential ... #causes #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology ... #diagnosis #management