18 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Intravascular Hemolysis ... • PCH • PNH ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Extravascular Causes ... hemoglobinuria (PNH ... Extravascular #Causes ... differential #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Lymphoid (ALL) - PAS ... Lymphadenopathy, CNS ... @AmyChung #Blood ... #Disorders #hematology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... - Water - Pus ... - Blood • Pleura ... syndrome Other Causes ... Transverse myelitis • Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Liver Disease, PNH ... - Peripheral Blood ... Urobilinogen #Hemolysis ... Differential #Diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Immunoglobulin M (IgM) • Blood ... influenza (younger pts ... disease (younger pts ... sensitize red blood ... #anemia #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... hemorrhage and hemolysis ... of Peripheral blood ... hematuria (without casts ... Diagnosis #Workup #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
defects. 1) HELLP (Hemolysis ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
defects. 1) HELLP (Hemolysis ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table