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diagnosis differential hemolytic oncology deficiency dermatology extravascular generalized iron product reactions secondary systemic treatment agglutinin alkaline alp antibody aplastic autoimmune
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... • PCH • PNH ... anemia • ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... anemia): ... #Hemolytic #Intravascular ... #diagnosis #hematology ... #anemia
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... TSAT, sTfR • Blood ... • Iron loss: Intravascular ... ) hemolysis, Intensive ... #ferritin #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
AIHA • Anemia ... type ± C3d • Blood ... 2) LOOK FOR a cause ... #management #treatment ... #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Systemic and Primary Causes ... / Systemic == Blood ... renal failure/uremia ... #causes
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... reflection of intravascular ... of Peripheral blood ... anemia Indirect ... Diagnosis #Workup #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
anemia • Cold ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... the RBCs causing intravascular ... #anemia #hematology
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... • Blood loss: ... • Iron loss: Intravascular ... hemolysis, (PNH ... #Fe #algorithm
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Blood Glucose ... renal failure/uremia ... #generalized #dermatology ... #causes
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... ABO incompatible blood ... Treat primary cause ... #treatment #management ... #hematology
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