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diagnosis algorithm anemia hemolytic liver classification extravascular injury intravascular oncology transaminitis ascites chemistry dermatology disorders hepatitis hodgkins interpretation lymphoma management
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
/uL Initial Workup ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... Diagnosis #Algorithm #hematology ... #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Approach to Anemia - Differential ... -100): • Non-hemolytic ... anemia, CKD • Hemolytic ... PK, HbC, HbSS, PNH ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... • PCH • PNH ... Extravascular #Differential ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... gastric bypass), LFT ... or if a primary hematologic ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Corpuscular Volume (MCV ... ) - Differential ... Bleed • Hemolysis ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... ) - Differential ... • Bleeding • Hemolysis ... #Hematology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Infection (EBV/CMV ... 2-5x normal - Hemolysis ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... platelet decrease - PNH ... #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
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