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diagnosis differential management anemia aflp algorithm blood comparison gastroenterology hellp hemolysis obstetrics pregnancy product reactions rheumatology table thrombocytopenia ttphus acidosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... uremic syndrome ... hemoglobinuria (PNH ... differential #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... : • Liver disease ... udaygulati #Hemolytic ... #classification ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... Renal Disease, Liver ... #Anemia #MCV #Classification ... #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... defects. 1) HELLP (Hemolysis ... child * Severe cases ... AFLP #obstetrics #hematology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Common Etiologies ... Nonalcoholic fatty liver ... disease (Budd-Chiari syndrome ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Disease, PNH ... Differential #Diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome ... deficiency • Liver ... deficiencies - PNH ... Differential #Diagnosis #hematology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... defects. 1) HELLP (Hemolysis ... , Elevated Liver ... child * Severe cases ... Obstetrics #OBGyn #Hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
Inherited Non-hemolytic ... population • Most common ... or liver injury ... and stress may cause ... Congenital #bilirubin #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... • Hemolysis ... diagnosis #algorithm #hepatology
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