37 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... purpura/hemolytic ... uremic syndrome ... How to approach thrombocytopenia ... , Hematology 2012
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... uremic syndrome ... hemoglobinuria (PNH ... differential #diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... defects. 1) HELLP (Hemolysis ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Intravascular Hemolysis ... • PCH • PNH ... Diagnosis #Algorithm #Causes ... #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Pregnancy Three syndromes ... defects. 1) HELLP (Hemolysis ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
: - Thrombocytopenia ... DIC/TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome ... deficiencies - PNH ... Differential #Diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Non-lmmune: • HELLP Syndrome ... Heart Valve) #Thrombocytopenia ... Diagnosis #Algorithm #Causes ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... platelet decrease - PNH ... Schistocytes, thrombocytopenia ... ARUPConsult @ARUPLabs #Hemolytic ... Algorithm #workup #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... spherocytosis, Hemolytic ... uremic syndrome ... Thrombotic idiopathic thrombocytopenia ... #differential #hematology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Production • Hemolysis ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia