86 results
diagnosis differential algorithm treatment rheumatology anemia syndrome workup dermatology oncology classification hemolysis hepatitis liver blood encephalopathy hepatic injury intravascular neurology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... idiopathic) - Autoimmune ... Extravascular #Causes ... differential #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Cold AIHA • Alloimmune ... • PCH • PNH ... Diagnosis #Algorithm #Causes ... #Hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Cold Agglutinin Disease ... MatthewHoMD #Autoimmune ... #Hemolytic #Anemia ... Diagnosis #Table #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... esp if severe disease ... BrighamMedRes #AIHA #Autoimmune ... AIHA #Treatment #management ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... 2) LOOK FOR a cause ... Warm #Antibody #Autoimmune ... #diagnosis #management ... #treatment #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... platelet decrease - PNH ... elliptocytosis, autoimmune ... @ARUPLabs #Hemolytic ... Algorithm #workup #hematology
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
DAT Results in Autoimmune ... Hemolysis DAT ... Cold agglutinin disease ... antiglobulin #test #DAT #Autoimmune ... #Hemolysis #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
-100): • Non-hemolytic ... PK, HbC, HbSS, PNH ... - Extrinsic: Autoimmune ... Non-megaloblastic: Liver disease ... Differential #Diagnosis #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Microangiopathic hemolytic ... Microspherocytes: Autoimmune ... hemolytic anemia ... cells: Sickle cell disease ... Smear #Analysis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... , Drugs, Liver Disease ... , PNH 3) Internal ... Differential #Diagnosis #hematology
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