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diagnosis algorithm coagulation management aptt ascites cirrhosis hepatitis hodgkins intravascular liver lymphoma polycythemia prolonged pt workup aflp anemia apml arterial
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Erythrocytosis) - Differential ... Splenomegaly, Increased PMNs ... Erythrocytosis #Differential ... #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Intravascular Hemolysis - Differential ... Drug-induced AIHA - Abnormal ... • PCH • PNH ... #Hematology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Causes of Ascites ... Normal Peritoneum ... peritonitis #Ascites #Causes ... #diagnosis #differential ... #hepatology #SAAG
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
imaging: Normal ... • Histology: Normal-mild ... Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential #
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... amyloidosis #Abnormal ... #hematology #coagulation
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiencies - PNH ... Cholesterol emboli • Septic ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
dysfunction (25%) • Hepatic ... Treat primary cause ... 100mg/dL) - Heparin ... Coagulation #diagnosis #causes ... treatment #management #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... pathophysiology #hematology ... #differential #
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... also arise in normal ... #oncology #diagnosis ... #differential # ... hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... e.g. heparin ... Jcortesizaguirr #Abnormal ... #diagnosis #differential ... #hematology #coagulation
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