17 results
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized ... , Breast) • Cancer ... Infection • Cancer ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... VTE #Malignancy #Cancer ... Anticoagulation #Management #Hematology ... #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
incidental DVT or PE in cancer ... thrombosis in cancer ... VTE #Malignancy #Cancer ... Anticoagulation #Management #Hematology ... #Oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Manifestations of DIC: • Petechiae ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Significant ↓ PLT: Petechiae ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... with pulmonary edema ... : No • Treatment ... Transfusion #Reactions #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... myalgias, HoTN, edema ... Renal Failure Treatment ... diagnosis #management #hematology ... #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... mucosal bleeding (Petechial ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology