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diagnosis rheumatology treatment syndrome antinxp2 antinxp2dm atlas basics cerebritis cns coagulation dermatomyositis dic disseminated diuresis diuretics dress effects erythematosus excretion
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Normal Saline (NS ... Composition of NS ... Normal Saline (NS ... Normal #Saline #NS ... #comparison #pharmacology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
• Facial Edema ... in 70% of cases ... withdrawal • Mild disease ... DRESS #Syndrome #dermatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Acute pulmonary edema ... Kidney stones caused ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Severe Liver Disease ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
S/Sx: Most pts ... only if no clear cause ... Bicarb<22) - avoid NS ... caution in HTN & edema ... Treatment #potassium #nephrology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... #Diagnosis #Management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... osteoarticular and skin disease ... #diagnosis #management ... #Dermatology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... directly by the disease ... specific to a single disease ... area of dermal oedema ... #Diagnosis #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
(depending on CNS ... or autoimmune disease ... for refractory disease ... HLH #Treatment #management ... #hematology
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