16 results
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm
Congenital
Medications
 • Anticonvulsants
 • Antibiotics
 • Antithyroid
 • Antihypertensive
Causes of Isolated ... Algorithm Congenital Medications ... Destruction • Systemic ... Lupus Erythematosus ... #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... autoantibodies that will cause ... RheumOnePagers) #Systemic ... #rheumatology # ... cerebritis #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... lower extremity edema ... • May involve PNS ... activation and/or medications
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... the face (many differential ... rosacea) 3) Limb oedema ... #system #erythematosus ... #rheumatology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
pulse pressure: systolic ... effusions). 1/5 pts ... endomyocardial biopsy Pharmacology ... heartfailure #diagnosis #management ... #cardiology #pharmacology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... • Facial Edema ... in 70% of cases ... Resolution > 15 days Differentials ... #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Reversible course Differential ... Electrolyte abnormality, Medication ... the underlying cause ... with AEDs until cause ... Syndrome #diagnosis #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... Na delivery): CHF ... only if no clear cause ... STOP offending medications ... caution in HTN & edema
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Drug Induced Systemic ... Lupus Erythematosus ... #medications #drugs ... #pharmacology # ... risk #differential