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diagnosis treatment lupus cardiology algorithm comparison differential erythematosus syndrome systemic blood cardiomyopathy cerebritis clinical cns coagulation criticalcare decisionaid deficiencies deficiency
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Summary • Epidemiology ... Positive in 60-80% of cases ... Usual therapeutic management ... #Summary #rheumatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... celiac disease, CF ... RA, SLE), Post-partum ... #table #comparison ... #diagnosis #hematology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels ... #lupus #management
Managing warfarin INR Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology # ... #medications #table ... #decisionaid #cardiology ... #hematology #warfarin
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... Erythematosus #SLE ... #rheumatology # ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... #comparison #table ... #rheumatology # ... diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... exclude other causes ... May have typical HF ... , LE edema • Minority ... Delivery • Stable
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... blisters containing pus ... Rule out other causes ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
S/Sx: Most pts ... Na delivery): CHF ... only if no clear cause ... and Elimination (see ... Table below)
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