17 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... hemoglobinuria (PNH ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel Syndrome ... (IBS) - Management ... and Hepatology ... #Management #gastroenterology ... #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... Diagnosis and Management ... and Hepatology ... #gastroenterology ... #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
+ Bleeding Treatment ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... - Lupus - Leukemia ... Treatment: - Systemic ... #diagnosis #dermatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
blisters containing pus ... Rule out other causes ... and lower jaw Treatment ... diagnosis #management ... #Dermatology