20 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... #hematology #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenic fever) Complications ... progress to MDS or acute ... leukemia • Associated ... PNH SCVMC Internal ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... -> AML: Blast crises ... - infiltrates (anemia ... Transformation: • Complication ... #Hematology #Oncology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
for Standard-Risk ... Acute Lymphoblastic ... Leukemia Induction ... Consolidation & CNS ... #oncology #pediatrics
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
5) Symptoms of anemia ... thrombocytopenia Complications ... chemotherapy for low-risk ... marrow failure with anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... and petechiae Causes ... virus (EBV) • Leukemia ... Treatment: ... #oncology #hematology
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework

IATROGENIC DISEASE
Secondary to invasive cardiac procedures

NONIATROGENIC
• Malignancy (e.g., metastatic spread:
cancer, lymphoma, leukemia ... carcinomas) • Complications ... of acute myocardial ... OTHER RARE CAUSES ... Differential #Diagnosis #cardiology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
carries a variable risk ... • Hairy Cell Leukemia ... and reducing the risk ... Syndromes #diagnosis #hematology ... #oncology