32 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... diagnosis and risk-stratification ... • Risks: infection ... only curative treatment ... #hematology #oncology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
patients at high risk ... also balance the risk ... VTE and bleeding complications ... Anticoagulation #Management #Hematology ... #Oncology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Treatment Schema ... for Standard-Risk ... Consolidation & CNS ... Cytarabine #ALL ... #timeline #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count ↑ PLT • ↑ PBS ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... prematurely • risk ... membrane into the CNS ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
→ Inflammation causes ... functional ID) Treatment ... showed reduced risk ... composite endpoint of all-cause ... diagnosis #management #cardiology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
thrombocytopenia Complications ... transformation) Treatment ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... considered in all ... cardiovascular risk ... coagulation and other causes ... pathophysiology #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Attempt if high risk ... diagnosis #management #hematology ... #oncology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
of hospitalized pts ... Lowest Risk: Tetracyclines ... - produced by all ... CT A/P: Assess complications ... KUB ↓↓Sens for complications