27 results
diagnosis management algorithm leukemia syndrome workup arteritis cancer chronic differential gca giantcell hemeonc lymphocytic mds myelodysplastic 2ndline anemia anthracycline anticoagulation
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... -> AML: Blast crises ... Transformation: • Complication ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Risks: infection ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... kinase (BTK) Complications ... leukemia • GI complications ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
megaloblastic anemia Treatment ... Consider stem cell ... neutropenic fever) Complications ... • Associated PNH ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
thrombocytopenia Complications ... chemotherapy for low-risk ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
patients at high risk ... also balance the risk ... VTE and bleeding complications ... Anticoagulation #Management #Hematology ... #Oncology
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Venous Catheters (CVL ... Other hardware - Risk-Benefit ... Consider: Spine, CNS ... #candidiasis #treatment ... #fungal #fungemia
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Acquired Risk ... considered in all ... cardiovascular risk ... coagulation and other causes ... pathophysiology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Attempt if high risk ... diagnosis #management #hematology ... #oncology
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
Treatment of giant ... cell arteritis ... day • Ischemic complications ... MTX or TCZ in case ... #Indications #rheumatology
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