53 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Clinical Findings Risk ... Apolipoprotein E4 allele Risk ... / Complications ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
invade URT & via hematologic ... hemorrhagic rash; symptoms ... CNS and hematologic ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... improvement in symptoms ... showed reduced risk ... heartfailure #diagnosis #management ... #cardiology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... neutropenic fever) Complications ... • Associated PNH ... Anemia #diagnosis #management ... #treatment #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... = nonspecific (nausea ... Monitor and Treat Complications ... #pathophysiology
Post-MI Free Wall Rupture
1. What's the role of revascularization when presenting with late STEMI?
2. What are
What are some causes ... What are the risk ... pursue surgical management ... FreeWall #Rupture #cardiology ... #complications
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
Candidemia Workup and Management ... minimum (if no complications ... Other hardware - Risk-Benefit ... workup dictated by symptoms ... Consider: Spine, CNS
Hypertrophic Cardiomyopathy (HOCM) - Diagnosis and Management
Diagnosis
 1. Wall thickness 215 mm (TTE/CT/MRI) 
 2. Absence
Diagnosis and Management ... Absence of Secondary Cause ... on MRI) Four P's ... Prevention - Prevent Symptoms ... #Cardiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... cardiovascular risk ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
transfused patientsl • Risk ... blood donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... Transfusion #Reactions #hematology