43 results
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
incidental DVT or PE in cancer ... thrombosis in cancer ... patients at high risk ... also balance the risk ... Anticoagulation #Management #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... diagnosis and risk-stratification ... • Risks: infection ... only curative treatment ... #hematology #oncology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... • No bleeding risk ... validated for VTE treatment ... studies suggest net clinical ... Anticoagulation #Factors #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Patient risk stratification ... algorithm for the treatment ... of cancer-associated ... VTE #Malignancy #Cancer ... Anticoagulation #Management #Hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
factors: Critical ... without other cause ... : 33% • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... by a hemophilia treatment ... center. ... that ↑ bleeding risk ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... cardiovascular risk ... coagulation and other causes ... - COVID-19 - PNH ... pathophysiology #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... Puncture, EEG Treatment ... #neurology #rheumatology ... diagnosis #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... Chemotherapy #Oncology #Hematology ... #Interactions #Table