31 results
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... - Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia •
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... cytopenias (usually anemia ... #treatment #hematology ... #oncology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Autoimmune Hemolytic Anemia ... DIAGNOSE AIHA • Anemia ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... • Associated PNH ... #diagnosis #management ... #treatment #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... - Hemolytic anemia ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology #
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... • PCH • PNH ... immune-complex hemolytic anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... hemoglobinuria (PNH ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
40 ml/min A - Anemia ... Causes of false- ... amyloidosis Other causes ... MGUS #diagnosis #hematology ... #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... Erythematosus #SLE #CNS ... #neurology #rheumatology ... cerebritis #diagnosis #management