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diagnosis differential algorithm management oncology mds myelodysplastic treatment abnormalities aids approach breathing classification dyspnea erythrocytosis extravascular hemolysis hiv infections infectiousdiseases
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... • Marrow Aplasia ... (MAHA) - Abnormal ... Diagnosis #Algorithm #Causes ... #Hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... • Associated PNH ... Medicine @SCVMCMed #Aplastic ... management #treatment #hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Water - Pus ... Barre - ALS - Transverse ... myelitis • Hematology ... : - Anemia • ... #pulmonary
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBC Production - Normal ... Deficiency • Aplastic ... Anemia • Anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... syndrome (MDS) (normal ... #hematology #diagnosis
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Splenomegaly, Increased PMNs ... Cyanosis without Pulmonary ... Apnea • Chronic Pulmonary ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... ) -plastic (shape ... old, ~10,000 new cases ... cytopenias (usually anemia ... Management #treatment #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Drug-induced AIHA - Abnormal ... • PCH • PNH ... immune-complex hemolytic anemia ... #Hematology
Abnormalities in Rate and Rhythm of Breathing Normal The respiratory rate is about 14—20 per min
the midbrain or pons ... heart failure, uremia ... punctuated by frequent sighs ... Occasional sighs ... Breathing #Patterns #Pulmonary
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... • Anemia • Aplastic ... Syndromes #diagnosis #hematology
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