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diagnosis differential anemia hemolytic intravascular dermatology extravascular arterial classification clots coagulation disseminated management nonpalpable palpable petechiae petechial physicalexam purpura rash
Hemolytic Anemia - Hemolysis Diagnostic Workup Infographic by: Howard Ong #Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... Workup Infographic ... #Algorithm #MAHA ... #TTP #Diagnosis ... #Workup #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... • PCH • PNH ... Shearing • MAHA ... (TTP, DIC, HUS) ... #Causes #Hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... neoplasms - PNH ... - HIT - MAHA ... : TTP, HUS, DIC ... Diagnosis #clots #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation (DIC ... thrombocytopenic purpura (TTP ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Fragmentation - MAHA ... : TTP, HUS, DIC, ... Liver Disease, PNH ... Differential #Diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... : • MAHA: TTP, ... HUS, DIC, HELLP ... udaygulati #Hemolytic ... classification #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... platelet decrease - PNH ... thrombocytopenia - DIC ... , TTP, HELLP, HUS ... #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/TTP/HUS - Hemolytic ... , TTP/HUS • Anticoagulants ... deficiencies - PNH ... Differential #Diagnosis #hematology ... #rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• TMA’s (HUS/TTP ... /DITMA) - MAHA ... : TTP/HUS > DIC ... Treat primary cause ... treatment #management #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... fulminans - DIC ... Autoimmune Vasculitis (lupus ... deficiency Work ... #Causes #dermatology
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