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diagnosis hematology algorithm causes management hemolytic workup oncology pathophysiology liver pulmonary treatment atlas cirrhosis disease hemolysis intravascular laboratory lfts macrocytic
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... Decreased RBC ... Infiltration Increased RBC ... Thalassemia • RBC ... Disorder • RBC
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... Microcytic RBC: ... disease, McLeod blood ... #Morphology #differential
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... • Extrinsic RBC ... • Intrinsic RBC ... #Differential # ... Diagnosis #Algorithm #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... #Differential # ... Algorithm #Causes #Hematology
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
== Decreased RBC ... Glucose Content • RBC ... Reduction == Increase RBC ... turnover • Acute blood ... Dilutional Effect • RBC
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... 3) Internal (RBC ... Defects: Sickle cell anemia ... - Peripheral Blood
Pathophysiology of Hemolytic Anemia - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects) -
Pathophysiology of Hemolytic Anemia ... - Defects in RBC ... - Defects in RBC ... Pathophysiology #Hemolytic #Anemia ... #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... coagulopathy (DIC) #RBC ... key #diagnosis #differential ... #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Volume (MCV) - Differential ... - Fe/TlBC, MCV/RBC ... Causes: Chronic Blood ... TIBC Normal - MCV/RBC ... inclusions in RBC
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(MCV): Average RBC ... wide range of RBC ... in peripheral blood ... High in acute blood ... Diagnosis #Workup #Hematology
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