347 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SLE ... pattern: - SjS, SLE ... Sm/RNP, Scl-70, SSA ... -52 (Ro52), SSA- ... body-like: - Neurologic
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
cytoplasmic antibodies; SLE ... Glomerulonephritis #Algorithm ... #Nephrology #Peds
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Diffuse) Anti-Sm - SLE ... Anti-SSA (Ro),
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
activity Anti-Ro/SSA ... manifestations • Neonatal SLE ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE
Algorithmic Approach to the Patient with Azotemia

#Azotemia #AKI #Nephrology #Diagnosis #Differential #Algorithm #Management
Algorithmic Approach ... Azotemia #AKI #Nephrology ... #Differential #Algorithm
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... lupus (90%) Anti-SSA ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE
Causes of Polyneuropathy - Differential Diagnosis Algorithm
 • Metabolic: DM, Hypothyroidism, CKD, Cirrhosis, Nutritional deficiency
 •
Differential Diagnosis Algorithm ... Paraneoplastic, CTD (SLE ... Differential #Diagnosis #Algorithm ... #causes #neurology
Kidney Biopsy - Diagnosis Algorithms
1) Normal Glomerulus by LM
2) Glomerular Crescents
3) Double Contours of GBM
4) Endocapillary
Biopsy - Diagnosis Algorithms ... renal #Diagnosis #Algorithm ... #nephrology #pathology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... Anti-Smith, Anti-Ro (SSA ... Syndrome: Anti-Ro (SSA
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... Leaning Tower of Pisa ... FatimahDandan #Pisa ... PhysicalExam #clinical #neurology