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clinical physicalexam neurology ophthalmology ocular msk orthopedics sports diagnosis test sign slitlamp cardiology pocus pulmonary ultrasound pediatrics fundoscopy management differential
Cephalosporin Coverage by Generation - HENPECKS Mnemonic 1st Gen: PEK (Proteus, E. coli, Klebsiella) 2nd Gen: HNPEK (Add
Ceftazidime: HENPECKS + PsA ... Streptococcus and MSSA ... Cefepime: HENPECKS + PSA ... Streptococcus and MSSA ... Add MRSA; Lose PSA
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Diffuse) Anti-Sm - SLE ... Anti-SSA (Ro),
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
activity Anti-Ro/SSA ... manifestations • Neonatal SLE ... dysmotility • MCTD (SLE ... • Specific for SLE ... Erythematosus #SLE
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Association with both SLE ... lupus (90%) Anti-SSA ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
pattern: - SLE ... pattern: - SjS, SLE ... Sm/RNP, Scl-70, SSA ... -52 (Ro52), SSA- ... Speckled: - SLE
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus (SLE ... Anti-Smith, Anti-Ro (SSA ... Syndrome: Anti-Ro (SSA
Parasternal Short-Axis (PSSA) view with right ventricle (RV), circular left ventricle (LV), and papillary muscles #Clinical
Parasternal Short-Axis (PSSA
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... Leaning Tower of Pisa ... FatimahDandan #Pisa ... neurology #posture #video
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 Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... Anti-ENA - Rare (SSA ... Erythematosus (SLE ... are evocative of SLE ... management of SLE
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