54 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #Management #treatment ... #hematology #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Differential #Diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #diagnosis #management ... #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Myelofibrosis Infectious ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... antibiotics are the most ... #hematology #anemia
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute infection ... malignancies • Anemia ... sarcoidosis) • Post-splenectomy ... Myelodysplastic syndrome ... #Causes #hematology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Aerosol is the most ... common route of infection ... Cardiopulmonary Syndrome ... #management #treatment ... #microbiology #infectiousdiseases
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... Treatment: ... #oncology #hematology ... #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... • Symptoms of anemia ... anemia • Cold ... Polyclonal IgM post ... #hematology #diagnosis
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
and Management ... Most invasive infections ... this morphology Treatment ... #Management #treatment ... #fungal #infectiousdiseases