20 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Defects Bernard-Soulier ... Syndrome • Defect ... Thrombasthenia • Defect ... #table #differential ... #diagnosis #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... with qualitative defects ... #disorders #hematology ... #hemepath #differential
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Features of hematologic ... anemia, ↑ MCV, ↑/↓ platelets ... Matthew Ho, MD PhD ... #Leukocytosis #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Count - Differential ... Matthew Ho, MD PhD ... Thrombocytosis #Platelets ... #Differential #
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia - Differential ... Matthew Ho, MD PhD ... Thrombocytopenia #Differential ... Diagnosis #Algorithm #hematology ... #platelets
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias - Differential ... : Membrane defects ... Matthew Ho, MD PhD ... Hemolytic #Anemias #Differential ... Diagnosis #Algorithm #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... Defects/Quantity ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Anemia (AIHA) - Differential ... Diagnosis Table ... Matthew Ho, MD PhD ... #Diagnosis #Table ... #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
with coagulation defects ... Liver tests, Low Platelets ... Severe coagulation defects ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... - Quantitative Defect ... Sequestration Disordered Platelet ... - Qualitative Defect ... Algorithm #Causes #Hematology