12 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis Table ... • Thrombotic Thrombocytopenic ... Matthew Ho, MD PhD ... Microangiopathy #TMA #hematology ... #differential #
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... TTP/HUS, HELLP ... Liver tests, Low Platelets ... AFLP #obstetrics #hematology ... #diagnosis #table
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP VS HUS ... Often hard to differentiate ... #thrombocytopenia ... Comparison #Diagnosis #Table ... #Hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... - Differential ... Matthew Ho, MD PhD ... Diagnosis #Algorithm #hematology ... #platelets
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Liver tests, Low Platelets ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... chain IIA • Thrombocytopenia ... Defects #comparison #table ... #differential # ... diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... disease - DIC/TTP/HUS ... : • DIC, TTP/HUS ... #Diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... Microangiopathy: DIC, TTP, HUS ... antiphospholipid syndrome - Pregnancy ... Diagnosis #Framework #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
triad of MAHA + thrombocytopenia ... TTP (atypical HUS ... Cr>2.3 & platelets ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... with or without platelet ... Schistocytes, thrombocytopenia ... DIC, TTP, HELLP, HUS ... Algorithm #workup #hematology