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diagnosis rheumatology differential lupus management druginduced erythematosus systemic treatment workup anemia bcnie bloodculture causes clinicopathology comparison criteria dil disorders endocarditis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... pericarditis • Hematologic ... > 0.5 g/24 hr, Class ... lupus nephritis, Class ... #Criteria #SLE
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... in >90% - Low ... 60-80% - Low ... #comparison #table ... #rheumatology #
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... Low Mean Corpuscular ... #Anemia #MCV #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Positive in 60-80% of cases ... 60-80% - Low ... • Evolution: ... Management #Summary #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... renal histological evaluation ... severity (ISN/RPS classification ... by 12 months Classification ... treatment #management #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... B-Cell ~90% • Low ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... Better call hematology ... some time, let’s see ... levels: realllly low ... #workup #hematology
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
or fungi (grows slow ... BCNIE relies on evaluation ... but important causes ... See charts - ... PCR for specific pathogens
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Preoperative Risk Evaluation ... ASA class If ... event, follow ACC algorithm ... Orthopedic • Low ... perioperative #Risk #Evaluation
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... • Complement (Low ... vasculitis, and SLE ... differential #diagnosis #rheumatology ... #classification
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