16 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential ... , Microangiopathic ... #Anemias #Differential ... #hematology
Anemia - Hemolysis Diagnostic Algorithm
Autoimmune hemolytic anemia
Microangiopathic hemolytic anemia
Probable thalassemia

Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis ... anemia Microangiopathic ... hemolytic anemia ... #Anemia #Algorithm ... #differential #
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... • Thrombotic microangiopathies ... Drug-induced thrombotic microangiopathy ... hemolytic anemia ... #diagnosis #hematology
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 • Membrane
 • Internal
    - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Environment - Microangiopathic ... #Anemia #Differential ... Diagnosis #Causes #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
findings in microangiopathic ... hemolytic anemia ... Microangiopathic ... hemolytic anemia ... #Hematology #Pathology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Mechanical Trauma (Microangiopathic ... hemolytic anemia ... - Thrombotic microangiopathy ... Extravascular #Causes #differential ... #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... • Peripheral blood ... Schistocytes DAT(-) → Microangiopathic ... hemolytic anemia ... #Anemia #Differential
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... Fragments • Microangiopathic ... Hemolytic Anemias ... #Causes #Hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Schistocytes: Microangiopathic ... hemolytic anemia ... #Peripheral #Blood ... Smear #Analysis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Retroperitoneal, Uterine • Hemolysis ... : Autoimmune, Microangiopathic ... hemolytic anemia ... Production #Index #hematology ... #anemia #differential